Biological and Immunological Characterization of a Functional L-HN Derivative of Botulinum Neurotoxin Serotype F

Botulinum neurotoxins (BoNTs) can cause nerve paralysis syndrome in mammals and other vertebrates.BoNTs are the most toxic biotoxins known and are classified as Class A biological warfare agents.BoNTs are mainly divided into seven serotypes A-G and new neurotoxins BoNT/H and BoNT/X, which have similar functions.BoNT proteins are 150 kDa polypeptide

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Experimental study of the effectiveness of the removal of virus hepatitis B, C and parvovirus B19 by the fractionation of blood plasma with ethanol

The purpose of the study was to assess the effectiveness of the removal of nucleic acids (NA), Hepatitis B (HBV) and C (HCV) viruses and parvovirus B19 (B19V) from blood plasma fractions obtained by alcohol separation.The studies were performed in a model experiment by fractionation normal pool plasma donation contaminated with virus-containing sam

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